About
K-Longevity is a nutraceutical created by PersonGene, a spin-off of the University of Bari, with an innovative formulation based on three compounds that have proven effective in delaying cellular senescence (cell aging) and overall manage to provide an anti-aging, energizing and antioxidant effect.
Aging is characterized by a gradual decline in function. In mammals, aging occurs heterogeneously across multiple organ systems, causing progressive deterioration that ultimately results in tissue dysfunction. As we age, our cells age and become increasingly subject to oxidative stress, losing the ability to respond to external insults and repair damage.
The K-longevity formulation contains a special Royal Jelly, because it is particularly enriched with 10-hydroxydecenoic acid (10-HDA).
This is a fatty acid naturally found in royal jelly that has been shown to have antiaging properties in several organisms, including humans.
The fatty acids contained in Royal Jelly are unique, that is, we find them only in this food and have been shown to possess various pharmacological properties: immunomodulatory, estrogenic, anti-inflammatory and epigenetic.
In addition to 10-HDA, Royal Jelly also contains Trans-10-hydroxy-Deacanoic acid (10-H2DA) 2 and nonanoic acid.
Laboratory experiments show that 10-HDA and nonanoic acid delay the senescence of our renal stem cells, which are critical for aging because they secrete high levels of the anti-aging protein Klotho that then passes into systemic circulation.
The anti-aging protein Klotho performs many important functions, limits aging and the development of chronic diseases through the regulation of phosphate and vitamin D metabolism. It works as a humoral factor also regulating oxidative stress and the sensitivity of cells to insulin.
Klotho also has important beneficial effects on the neuronal level and cognitive deficits.
Therefore, keeping our renal stem cells active by taking these two components to stimulate them to secrete Klotho can be important for the well-being of the entire organism.
NOI
In addition, some clinical research shows the ability of royal jelly to regenerate pancreatic cells, especially beta cells, and to reduce blood glucose. As a natural anabolic, its application has been observed in aging.
Royal Jelly also contains a large amount of vitamins and minerals such as vitamins B-1, B-2, B-3, B-6, with a predominance of pantothenic acid and, to a lesser extent, vitamins A, B-12, C, D and E.
Calcium, copper, iron, phosphorus, potassium, silicon and sulfur are also present. The high content of B vitamins, necessary for growth, for the health of the nervous and immune systems.
In addition K-Longevity also contains Vitamin A and Quercetin.
Vitamin A
Vitamin A (retinol, retinoic acid, retinaldehyde) is an important nutrient for vision, tissue growth and differentiation, cell division, reproduction, and immunity. It is also known for its antioxidant properties.
Vitamin A has been shown to be effective in regulating renal stem cells, inducing them to differentiate when necessary to replace damaged renal cells, and also contributes to the normal function of the immune system.
Quercetin is a flavonoid, a plant-based compound with strong antioxidant and anti-inflammatory properties.
Among the most common flavonoids, it can be isolated from numerous plant species: horse chestnut, marigold, hawthorn, chamomile, St. John's Wort and Ginkgo biloba.
Thanks to its antioxidant action, quercetin fights free radicals and oxidative stress at the cellular level.
Furthermore, its anti-inflammatory activity attenuates chronic and degenerative inflammatory processes.
Quercetin has a protective effect on kidney cells through anti-inflammatory and anti-fibrotic action. In addition, it has also proven effective in fighting cellular aging.
